Diabetes mechanism in obesity and more

Cardiovascular disease is caused by macrovascular disease. Diabetic foot, which is often caused by a combination of sensory neuropathy and vascular damage, increases the risk of diabetic foot ulcers and infection, as well as necrosis and gangrene in severe cases. Type 2 diabetes is linked to more macrovascular diseases than type 1 diabetes. Peripheral vascular disease and an increased risk of infection have serious consequences in the care of the critically ill patient. Diabetes increases the risk of liver, pancreas, and endometrial cancer by doubling the risk. It doubles the risk of colorectal, breast, and bladder cancer by 20% to 50%.

  • Cardiac complications
  • Macrovascular disease
  • Pathogenic mechanisms/ complications
  • Dyslipidaemia, lipoproteins
  • Endothelium
  • Animal models of complications
  • Other complications
  • Cancer
  • Cognitive dysfunction and Alzheimer Disease
  • Non-alcoholic fatty liver disease (NAFLD) including liver omics

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