Diabetes technology and Societal Impact
Chronic blood glucose elevation causes angiopathy, or damage to blood vessels. Because they do not require insulin, the endothelial cells that line the blood vessels absorb more glucose than normal. They then produce more surface glycoproteins than usual, causing the basement membrane to thicken and weaken. The problems that result are classified as "microvascular disease" due to damage to small blood vessels and "macrovascular disease" due to damage to arteries.
- Neuropathy: somatic
- Neuropathy: autonomic, incl. erectile dysfunction
- Diabetic foot and skin disorders
- Retinopathy
- Nephropathy
- Hypertension
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